diff --git a/src/wallet/sqlite.cpp b/src/wallet/sqlite.cpp
--- a/src/wallet/sqlite.cpp
+++ b/src/wallet/sqlite.cpp
@@ -50,6 +50,14 @@
                     strprintf("SQLiteDatabase: Failed to setup error log: %s\n",
                               sqlite3_errstr(ret)));
             }
+            // Force serialized threading mode
+            ret = sqlite3_config(SQLITE_CONFIG_SERIALIZED);
+            if (ret != SQLITE_OK) {
+                throw std::runtime_error(
+                    strprintf("SQLiteDatabase: Failed to configure serialized "
+                              "threading mode: %s\n",
+                              sqlite3_errstr(ret)));
+            }
         }
         // This is a no-op if sqlite3 is already initialized
         int ret = sqlite3_initialize();