diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -152,7 +152,7 @@
                                        #:key
                                        (base-gcc-for-libc base-gcc)
                                        (base-kernel-headers base-linux-kernel-headers)
-                                       (base-libc (hardened-glibc (make-glibc-without-werror glibc-2.27)))
+                                       (base-libc (hardened-glibc (make-glibc-without-werror glibc-2.28)))
                                        (base-gcc (make-gcc-rpath-link (hardened-gcc base-gcc))))
   "Convenience wrapper around MAKE-CROSS-TOOLCHAIN with default values
 desirable for building Bitcoin ABC release binaries."
@@ -549,23 +549,23 @@
     "--enable-stack-protector" "all")
     "--enable-bind-now" "yes"))
 
-(define-public glibc-2.27
+(define-public glibc-2.28
   (package
     (inherit glibc-2.31)
-    (version "2.27")
+    (version "2.28")
     (source (origin
               (method git-fetch)
               (uri (git-reference
                     (url "https://sourceware.org/git/glibc.git")
-                    (commit "73886db6218e613bd6d4edf529f11e008a6c2fa6")))
-              (file-name (git-file-name "glibc" "73886db6218e613bd6d4edf529f11e008a6c2fa6"))
+                    (commit "c9e58ae23402eb82877de90fd8a18519c086ed87")))
+              (file-name (git-file-name "glibc" "c9e58ae23402eb82877de90fd8a18519c086ed87"))
               (sha256
                (base32
-                "0azpb9cvnbv25zg8019rqz48h8i2257ngyjg566dlnp74ivrs9vq"))
+                "0wm0if2n4z48kpn85va6yb4iac34crds2f55ddpz1hykx6jp1pb6"))
               (patches (search-our-patches "glibc-ldd-x86_64.patch"
                                            "glibc-versioned-locpath.patch"
-                                           "glibc-2.27-fcommon.patch"
-                                           "glibc-2.27-guix-prefix.patch"))))))
+                                           "glibc-2.28-fcommon.patch"
+                                           "glibc-2.28-guix-prefix.patch"))))))
 
 (packages->manifest
  (append
diff --git a/contrib/guix/patches/glibc-2.27-fcommon.patch b/contrib/guix/patches/glibc-2.28-fcommon.patch
rename from contrib/guix/patches/glibc-2.27-fcommon.patch
rename to contrib/guix/patches/glibc-2.28-fcommon.patch
--- a/contrib/guix/patches/glibc-2.27-fcommon.patch
+++ b/contrib/guix/patches/glibc-2.28-fcommon.patch
@@ -21,7 +21,7 @@
 index 86a71e5802..aa2166be60 100644
 --- a/Makeconfig
 +++ b/Makeconfig
-@@ -896,7 +896,7 @@ ifeq	"$(strip $(+cflags))" ""
+@@ -901,7 +901,7 @@ ifeq	"$(strip $(+cflags))" ""
  endif	# $(+cflags) == ""
  
  +cflags += $(cflags-cpu) $(+gccwarn) $(+merge-constants) $(+math-flags) \
diff --git a/contrib/guix/patches/glibc-2.27-guix-prefix.patch b/contrib/guix/patches/glibc-2.28-guix-prefix.patch
rename from contrib/guix/patches/glibc-2.27-guix-prefix.patch
rename to contrib/guix/patches/glibc-2.28-guix-prefix.patch
--- a/contrib/guix/patches/glibc-2.27-guix-prefix.patch
+++ b/contrib/guix/patches/glibc-2.28-guix-prefix.patch
@@ -9,7 +9,7 @@
 
 --- a/Makeconfig
 +++ b/Makeconfig
-@@ -992,6 +992,10 @@ object-suffixes :=
+@@ -998,6 +998,10 @@ object-suffixes :=
  CPPFLAGS-.o = $(pic-default)
  # libc.a must be compiled with -fPIE/-fpie for static PIE.
  CFLAGS-.o = $(filter %frame-pointer,$(+cflags)) $(pie-default)
diff --git a/contrib/guix/patches/glibc-versioned-locpath.patch b/contrib/guix/patches/glibc-versioned-locpath.patch
--- a/contrib/guix/patches/glibc-versioned-locpath.patch
+++ b/contrib/guix/patches/glibc-versioned-locpath.patch
@@ -143,10 +143,10 @@
  
    if (category == LC_ALL)
 diff --git a/string/Makefile b/string/Makefile
-index 8424a61..f925503 100644
+index aa2da9ca72..f273c2611d 100644
 --- a/string/Makefile
 +++ b/string/Makefile
-@@ -38,7 +38,7 @@ routines	:= strcat strchr strcmp strcoll strcpy strcspn		\
+@@ -40,7 +40,7 @@ routines	:= strcat strchr strcmp strcoll strcpy strcspn		\
  		   swab strfry memfrob memmem rawmemchr strchrnul	\
  		   $(addprefix argz-,append count create ctsep next	\
  				     delete extract insert stringify	\
@@ -218,10 +218,10 @@
 +}
 +weak_alias (__argz_suffix_entries, argz_suffix_entries)
 diff --git a/string/argz.h b/string/argz.h
-index bb62a31..d276a35 100644
+index 9c496f5ef5..1010a439d8 100644
 --- a/string/argz.h
 +++ b/string/argz.h
-@@ -134,6 +134,16 @@ extern error_t argz_replace (char **__restrict __argz,
+@@ -108,6 +108,16 @@ extern error_t argz_replace (char **__restrict __argz,
  			     const char *__restrict __str,
  			     const char *__restrict __with,
  			     unsigned int *__restrict __replace_count);