diff --git a/cmake/platforms/OSX.cmake b/cmake/platforms/OSX.cmake
--- a/cmake/platforms/OSX.cmake
+++ b/cmake/platforms/OSX.cmake
@@ -14,7 +14,7 @@
 set(CMAKE_C_COMPILER_TARGET ${TOOLCHAIN_PREFIX})
 set(CMAKE_CXX_COMPILER_TARGET ${TOOLCHAIN_PREFIX})
 
-set(OSX_MIN_VERSION 10.15)
+set(OSX_MIN_VERSION 11.0)
 # OSX_SDK_VERSION 11.0
 # Note: don't use XCODE_VERSION, it's a cmake built-in variable !
 set(SDK_XCODE_VERSION 12.2)
diff --git a/contrib/devtools/symbol-check.py b/contrib/devtools/symbol-check.py
--- a/contrib/devtools/symbol-check.py
+++ b/contrib/devtools/symbol-check.py
@@ -250,7 +250,7 @@
 
 
 def check_MACHO_min_os(binary) -> bool:
-    return binary.build_version.minos == [10, 15, 0]
+    return binary.build_version.minos == [11, 0, 0]
 
 
 def check_MACHO_sdk(binary) -> bool:
diff --git a/contrib/devtools/test-symbol-check.py b/contrib/devtools/test-symbol-check.py
--- a/contrib/devtools/test-symbol-check.py
+++ b/contrib/devtools/test-symbol-check.py
@@ -208,7 +208,7 @@
                 cc,
                 source,
                 executable,
-                ["-Wl,-platform_version", "-Wl,macos", "-Wl,10.15", "-Wl,11.4"],
+                ["-Wl,-platform_version", "-Wl,macos", "-Wl,11.0", "-Wl,11.4"],
             ),
             (1, f"{executable}: failed SDK"),
         )
diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -617,5 +617,5 @@
           ((string-contains target "-linux-")
            (list (make-bitcoin-cross-toolchain target)))
           ((string-contains target "darwin")
-           (list clang-toolchain-10 binutils xorriso python-signapple))
+           (list clang-toolchain-11 binutils xorriso python-signapple))
           (else '())))))
diff --git a/depends/hosts/darwin.mk b/depends/hosts/darwin.mk
--- a/depends/hosts/darwin.mk
+++ b/depends/hosts/darwin.mk
@@ -1,4 +1,4 @@
-OSX_MIN_VERSION=10.15
+OSX_MIN_VERSION=11.0
 OSX_SDK_VERSION=11.0
 XCODE_VERSION=12.2
 XCODE_BUILD_ID=12B45b
diff --git a/depends/packages/native_clang.mk b/depends/packages/native_clang.mk
--- a/depends/packages/native_clang.mk
+++ b/depends/packages/native_clang.mk
@@ -1,8 +1,8 @@
 package=native_clang
-$(package)_version=10.0.1
+$(package)_version=11.1.0
 $(package)_download_path=https://github.com/llvm/llvm-project/releases/download/llvmorg-$($(package)_version)
 $(package)_file_name=clang+llvm-$($(package)_version)-x86_64-linux-gnu-ubuntu-16.04.tar.xz
-$(package)_sha256_hash=48b83ef827ac2c213d5b64f5ad7ed082c8bcb712b46644e0dc5045c6f462c231
+$(package)_sha256_hash=c691a558967fb7709fb81e0ed80d1f775f4502810236aa968b4406526b43bee1
 
 define $(package)_preprocess_cmds
   rm -f $($(package)_extract_dir)/lib/libc++abi.so*
diff --git a/share/qt/Info.plist.cmake.in b/share/qt/Info.plist.cmake.in
--- a/share/qt/Info.plist.cmake.in
+++ b/share/qt/Info.plist.cmake.in
@@ -3,7 +3,7 @@
 <plist version="0.9">
 <dict>
   <key>LSMinimumSystemVersion</key>
-  <string>10.15.0</string>
+  <string>11</string>
 
   <key>LSArchitecturePriority</key>
   <array>
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -160,7 +160,7 @@
 
 if(${CMAKE_SYSTEM_NAME} MATCHES "Darwin")
 	add_compile_definitions(MAC_OSX OBJC_OLD_DISPATCH_PROTOTYPES=0)
-	add_linker_flags(-Wl,-dead_strip_dylibs)
+	add_linker_flags(-Wl,-dead_strip_dylibs -Wl,-fixup_chains)
 endif()
 
 if(ENABLE_REDUCE_EXPORTS)