diff --git a/build-aux/m4/bitcoin_qt.m4 b/build-aux/m4/bitcoin_qt.m4
--- a/build-aux/m4/bitcoin_qt.m4
+++ b/build-aux/m4/bitcoin_qt.m4
@@ -116,24 +116,6 @@
   if test "x$bitcoin_cv_static_qt" = xyes; then
     _BITCOIN_QT_FIND_STATIC_PLUGINS
     AC_DEFINE(QT_STATICPLUGIN, 1, [Define this symbol if qt plugins are static])
-    AC_CACHE_CHECK(for Qt < 5.4, bitcoin_cv_need_acc_widget,[
-      AC_COMPILE_IFELSE([AC_LANG_PROGRAM([[
-          #include <QtCore/qconfig.h>
-          #ifndef QT_VERSION
-          #  include <QtCore/qglobal.h>
-          #endif
-        ]],
-        [[
-          #if QT_VERSION >= 0x050400
-          choke
-          #endif
-        ]])],
-      [bitcoin_cv_need_acc_widget=yes],
-      [bitcoin_cv_need_acc_widget=no])
-    ])
-    if test "x$bitcoin_cv_need_acc_widget" = xyes; then
-      _BITCOIN_QT_CHECK_STATIC_PLUGINS([Q_IMPORT_PLUGIN(AccessibleFactory)], [-lqtaccessiblewidgets])
-    fi
     _BITCOIN_QT_CHECK_STATIC_PLUGINS([Q_IMPORT_PLUGIN(QMinimalIntegrationPlugin)],[-lqminimal])
     AC_DEFINE(QT_QPA_PLATFORM_MINIMAL, 1, [Define this symbol if the minimal qt platform exists])
     if test "x$TARGET_OS" = xwindows; then
@@ -264,7 +246,7 @@
 dnl configure.ac.
 dnl ----
 
-dnl Internal. Check if the included version of Qt is Qt5.
+dnl Internal. Check included version of Qt against minimum specified in doc/dependencies.md
 dnl Requires: INCLUDES must be populated as necessary.
 dnl Output: bitcoin_cv_qt5=yes|no
 AC_DEFUN([_BITCOIN_QT_CHECK_QT5],[
@@ -276,7 +258,7 @@
       #endif
     ]],
     [[
-      #if QT_VERSION < 0x050000 || QT_VERSION_MAJOR < 5
+      #if QT_VERSION < 0x050501
       choke
       #endif
     ]])],
@@ -374,9 +356,7 @@
                 fi
        if test "x$TARGET_OS" = xlinux; then
          PKG_CHECK_MODULES([X11XCB], [x11-xcb], [QT_LIBS="$X11XCB_LIBS $QT_LIBS"])
-         if ${PKG_CONFIG} --exists "Qt5Core >= 5.5" 2>/dev/null; then
-           PKG_CHECK_MODULES([QTXCBQPA], [Qt5XcbQpa], [QT_LIBS="$QTXCBQPA_LIBS $QT_LIBS"])
-         fi
+         PKG_CHECK_MODULES([QTXCBQPA], [Qt5XcbQpa], [QT_LIBS="$QTXCBQPA_LIBS $QT_LIBS"])
        elif test "x$TARGET_OS" = xdarwin; then
          PKG_CHECK_MODULES([QTCLIPBOARD], [Qt5ClipboardSupport], [QT_LIBS="-lQt5ClipboardSupport $QT_LIBS"])
          PKG_CHECK_MODULES([QTGRAPHICS], [Qt5GraphicsSupport], [QT_LIBS="-lQt5GraphicsSupport $QT_LIBS"])
@@ -527,4 +507,3 @@
   CXXFLAGS="$TEMP_CXXFLAGS"
   LIBS="$TEMP_LIBS"
 ])
-
diff --git a/src/qt/CMakeLists.txt b/src/qt/CMakeLists.txt
--- a/src/qt/CMakeLists.txt
+++ b/src/qt/CMakeLists.txt
@@ -13,7 +13,7 @@
 	list(APPEND QT_REQUIRED_COMPONENTS DBus)
 endif()
 
-find_package(Qt5 COMPONENTS ${QT_REQUIRED_COMPONENTS} REQUIRED HINTS "${QT5_PREFIX}")
+find_package(Qt5 5.5.1 COMPONENTS ${QT_REQUIRED_COMPONENTS} REQUIRED HINTS "${QT5_PREFIX}")
 
 # Localisation
 add_subdirectory(locale)
diff --git a/src/qt/bitcoin.cpp b/src/qt/bitcoin.cpp
--- a/src/qt/bitcoin.cpp
+++ b/src/qt/bitcoin.cpp
@@ -50,9 +50,6 @@
 
 #if defined(QT_STATICPLUGIN)
 #include <QtPlugin>
-#if QT_VERSION < 0x050400
-Q_IMPORT_PLUGIN(AccessibleFactory)
-#endif
 #if defined(QT_QPA_PLATFORM_XCB)
 Q_IMPORT_PLUGIN(QXcbIntegrationPlugin);
 #elif defined(QT_QPA_PLATFORM_WINDOWS)
diff --git a/src/qt/test/apptests.cpp b/src/qt/test/apptests.cpp
--- a/src/qt/test/apptests.cpp
+++ b/src/qt/test/apptests.cpp
@@ -29,10 +29,8 @@
 #include <QTest>
 #include <QTextEdit>
 #include <QtGlobal>
-#if QT_VERSION >= 0x050000
-#include <QtTest/QtTestWidgets>
-#endif
 #include <QtTest/QtTestGui>
+#include <QtTest/QtTestWidgets>
 
 #include <univalue.h>
 
diff --git a/src/qt/test/rpcnestedtests.cpp b/src/qt/test/rpcnestedtests.cpp
--- a/src/qt/test/rpcnestedtests.cpp
+++ b/src/qt/test/rpcnestedtests.cpp
@@ -157,10 +157,6 @@
                                       "rpcNestedTest(   abc   ,   cba )");
     QVERIFY(result == "[\"abc\",\"cba\"]");
 
-#if QT_VERSION >= 0x050300
-    // do the QVERIFY_EXCEPTION_THROWN checks only with Qt5.3 and higher
-    // (QVERIFY_EXCEPTION_THROWN was introduced in Qt5.3)
-
     // invalid syntax
     QVERIFY_EXCEPTION_THROWN(RPCConsole::RPCExecuteCommandLine(
                                  *node, result, "getblockchaininfo() .\n"),
@@ -198,5 +194,4 @@
     QVERIFY_EXCEPTION_THROWN(RPCConsole::RPCExecuteCommandLine(
                                  *node, result, "rpcNestedTest(abc,,)"),
                              std::runtime_error);
-#endif
 }