diff --git a/src/test/uint256_tests.cpp b/src/test/uint256_tests.cpp
--- a/src/test/uint256_tests.cpp
+++ b/src/test/uint256_tests.cpp
@@ -280,15 +280,18 @@
     BOOST_CHECK(R2L.GetHex() == UintToArith256(R2L).GetHex());
 }
 
+// Use *& to remove self-assign warning.
+#define SELF(x) (*&(x))
+
 BOOST_AUTO_TEST_CASE(operator_with_self) {
     arith_uint256 v = UintToArith256(uint256S("02"));
-    v *= v;
+    v *= SELF(v);
     BOOST_CHECK(v == UintToArith256(uint256S("04")));
-    v /= v;
+    v /= SELF(v);
     BOOST_CHECK(v == UintToArith256(uint256S("01")));
-    v += v;
+    v += SELF(v);
     BOOST_CHECK(v == UintToArith256(uint256S("02")));
-    v -= v;
+    v -= SELF(v);
     BOOST_CHECK(v == UintToArith256(uint256S("0")));
 }