diff --git a/src/rpc/blockchain.cpp b/src/rpc/blockchain.cpp
--- a/src/rpc/blockchain.cpp
+++ b/src/rpc/blockchain.cpp
@@ -2198,6 +2198,12 @@
         do_mediantxsize || loop_inputs ||
         SetHasKeys(stats, "total_size", "avgtxsize", "mintxsize", "maxtxsize");
 
+    if (loop_inputs && !g_txindex) {
+        throw JSONRPCError(
+            RPC_INVALID_PARAMETER,
+            "One or more of the selected stats requires -txindex enabled");
+    }
+
     const int64_t blockMaxSize = config.GetMaxBlockSize();
     Amount maxfee = Amount::zero();
     Amount maxfeerate = Amount::zero();
@@ -2249,12 +2255,6 @@
         }
 
         if (loop_inputs) {
-            if (!g_txindex) {
-                throw JSONRPCError(RPC_INVALID_PARAMETER,
-                                   "One or more of the selected stats requires "
-                                   "-txindex enabled");
-            }
-
             Amount tx_total_in = Amount::zero();
             for (const CTxIn &in : tx->vin) {
                 CTransactionRef tx_in;
diff --git a/test/functional/rpc_getblockstats.py b/test/functional/rpc_getblockstats.py
--- a/test/functional/rpc_getblockstats.py
+++ b/test/functional/rpc_getblockstats.py
@@ -194,6 +194,8 @@
         assert_raises_rpc_error(-8, 'Invalid selected statistic aaa{}'.format(inv_sel_stat),
                                 self.nodes[0].getblockstats, hash_or_height=1, stats=['minfee', 'aaa{}'.format(inv_sel_stat)])
 
+        assert_raises_rpc_error(-8, 'One or more of the selected stats requires -txindex enabled',
+                                self.nodes[1].getblockstats, hash_or_height=1)
         assert_raises_rpc_error(-8, 'One or more of the selected stats requires -txindex enabled',
                                 self.nodes[1].getblockstats, hash_or_height=self.start_height + self.max_stat_pos)