diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -115,8 +115,15 @@
 	# Build all static so there is no dll file to distribute.
 	add_linker_flags(-static)
 
-	# Windows 7
-	add_compile_definitions(_WIN32_WINNT=0x0601)
+	add_compile_definitions(
+		# Windows 7
+		_WIN32_WINNT=0x0601
+		# Internet Explorer 5.01 (!)
+		_WIN32_IE=0x0501
+		# Define WIN32_LEAN_AND_MEAN to exclude APIs such as Cryptography, DDE,
+		# RPC, Shell, and Windows Sockets.
+		WIN32_LEAN_AND_MEAN
+	)
 endif()
 
 if(${CMAKE_SYSTEM_NAME} MATCHES "Darwin")
diff --git a/src/compat.h b/src/compat.h
--- a/src/compat.h
+++ b/src/compat.h
@@ -11,9 +11,6 @@
 #endif
 
 #ifdef WIN32
-#ifndef WIN32_LEAN_AND_MEAN
-#define WIN32_LEAN_AND_MEAN 1
-#endif
 #ifndef NOMINMAX
 #define NOMINMAX
 #endif
diff --git a/src/qt/guiutil.cpp b/src/qt/guiutil.cpp
--- a/src/qt/guiutil.cpp
+++ b/src/qt/guiutil.cpp
@@ -21,11 +21,6 @@
 #include <util/system.h>
 
 #ifdef WIN32
-#ifdef _WIN32_IE
-#undef _WIN32_IE
-#endif
-#define _WIN32_IE 0x0501
-#define WIN32_LEAN_AND_MEAN 1
 #ifndef NOMINMAX
 #define NOMINMAX
 #endif
diff --git a/src/support/lockedpool.cpp b/src/support/lockedpool.cpp
--- a/src/support/lockedpool.cpp
+++ b/src/support/lockedpool.cpp
@@ -10,7 +10,6 @@
 #endif
 
 #ifdef WIN32
-#define WIN32_LEAN_AND_MEAN 1
 #ifndef NOMINMAX
 #define NOMINMAX
 #endif
diff --git a/src/util/system.cpp b/src/util/system.cpp
--- a/src/util/system.cpp
+++ b/src/util/system.cpp
@@ -49,12 +49,6 @@
 #pragma warning(disable : 4717)
 #endif
 
-#ifdef _WIN32_IE
-#undef _WIN32_IE
-#endif
-#define _WIN32_IE 0x0501
-
-#define WIN32_LEAN_AND_MEAN 1
 #ifndef NOMINMAX
 #define NOMINMAX
 #endif