diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -1,3 +1,5 @@
 # Copyright (c) 2017 The Bitcoin developers
 
+add_subdirectory(config)
+add_subdirectory(crypto)
 add_subdirectory(univalue)
diff --git a/src/config/CMakeLists.txt b/src/config/CMakeLists.txt
new file mode 100644
--- /dev/null
+++ b/src/config/CMakeLists.txt
@@ -0,0 +1,49 @@
+# Copyright (c) 2017 The Bitcoin developers
+
+# This generates config.h which provides numerous defines
+# about the state of the plateform we are building on.
+
+include(CheckIncludeFiles)
+include(CheckSymbolExists)
+
+# Endianness
+check_include_files("endian.h" HAVE_ENDIAN_H)
+check_include_files("sys/endian.h" HAVE_SYS_ENDIAN_H)
+
+if(HAVE_ENDIAN_H)
+	set(ENDIAN_FILE "endian.h")
+elseif(HAVE_SYS_ENDIAN_H)
+	set(ENDIAN_FILE "sys/endian.h")
+else()
+endif()
+
+if(ENDIAN_FILE)
+	check_symbol_exists(htole16 ${ENDIAN_FILE} HAVE_DECL_HTOLE16)
+	check_symbol_exists(htobe16 ${ENDIAN_FILE} HAVE_DECL_HTOBE16)
+	check_symbol_exists(be16toh ${ENDIAN_FILE} HAVE_DECL_BE16TOH)
+	check_symbol_exists(le16toh ${ENDIAN_FILE} HAVE_DECL_LE16TOH)
+	check_symbol_exists(htobe32 ${ENDIAN_FILE} HAVE_DECL_HTOBE32)
+	check_symbol_exists(htole32 ${ENDIAN_FILE} HAVE_DECL_HTOLE32)
+	check_symbol_exists(be32toh ${ENDIAN_FILE} HAVE_DECL_BE32TOH)
+	check_symbol_exists(le32toh ${ENDIAN_FILE} HAVE_DECL_LE32TOH)
+	check_symbol_exists(htobe64 ${ENDIAN_FILE} HAVE_DECL_HTOBE64)
+	check_symbol_exists(htole64 ${ENDIAN_FILE} HAVE_DECL_HTOLE64)
+	check_symbol_exists(be64toh ${ENDIAN_FILE} HAVE_DECL_BE64TOH)
+	check_symbol_exists(le64toh ${ENDIAN_FILE} HAVE_DECL_LE64TOH)
+endif()
+
+# Byte swap
+check_include_files("byteswap.h" HAVE_BYTESWAP_H)
+
+check_symbol_exists(bswap_16 "byteswap.h" HAVE_DECL_BSWAP_16)
+check_symbol_exists(bswap_32 "byteswap.h" HAVE_DECL_BSWAP_32)
+check_symbol_exists(bswap_64 "byteswap.h" HAVE_DECL_BSWAP_64)
+
+# Bitmanip intrinsics
+check_symbol_exists(__builtin_clz "" HAVE_DECL___BUILTIN_CLZ)
+check_symbol_exists(__builtin_clzl "" HAVE_DECL___BUILTIN_CLZL)
+check_symbol_exists(__builtin_clzll "" HAVE_DECL___BUILTIN_CLZLL)
+
+
+# Generate the config
+configure_file(bitcoin-config.h.cmake.in bitcoin-config.h)
diff --git a/src/config/bitcoin-config.h.cmake.in b/src/config/bitcoin-config.h.cmake.in
new file mode 100644
--- /dev/null
+++ b/src/config/bitcoin-config.h.cmake.in
@@ -0,0 +1,32 @@
+// Copyright (c) 2017 The Bitcoin developers
+
+#ifndef BITCOIN_CONFIG_BITCOIN_CONFIG_H
+#define BITCOIN_CONFIG_BITCOIN_CONFIG_H
+
+#cmakedefine HAVE_ENDIAN_H @HAVE_ENDIAN_H@
+#cmakedefine HAVE_SYS_ENDIAN_H @HAVE_SYS_ENDIAN_H@
+
+#cmakedefine HAVE_DECL_HTOLE16 @HAVE_DECL_HTOLE16@
+#cmakedefine HAVE_DECL_HTOBE16 @HAVE_DECL_HTOBE16@
+#cmakedefine HAVE_DECL_BE16TOH @HAVE_DECL_BE16TOH@
+#cmakedefine HAVE_DECL_LE16TOH @HAVE_DECL_LE16TOH@
+#cmakedefine HAVE_DECL_HTOBE32 @HAVE_DECL_HTOBE32@
+#cmakedefine HAVE_DECL_HTOLE32 @HAVE_DECL_HTOLE32@
+#cmakedefine HAVE_DECL_BE32TOH @HAVE_DECL_BE32TOH@
+#cmakedefine HAVE_DECL_LE32TOH @HAVE_DECL_LE32TOH@
+#cmakedefine HAVE_DECL_HTOBE64 @HAVE_DECL_HTOBE64@
+#cmakedefine HAVE_DECL_HTOLE64 @HAVE_DECL_HTOLE64@
+#cmakedefine HAVE_DECL_BE64TOH @HAVE_DECL_BE64TOH@
+#cmakedefine HAVE_DECL_LE64TOH @HAVE_DECL_LE64TOH@
+
+#cmakedefine HAVE_BYTESWAP_H @HAVE_BYTESWAP_H@
+
+#cmakedefine HAVE_DECL_BSWAP_16 @HAVE_DECL_BSWAP_16@
+#cmakedefine HAVE_DECL_BSWAP_32 @HAVE_DECL_BSWAP_32@
+#cmakedefine HAVE_DECL_BSWAP_64 @HAVE_DECL_BSWAP_64@
+
+#cmakedefine HAVE_DECL___BUILTIN_CLZ @HAVE_DECL___BUILTIN_CLZ@
+#cmakedefine HAVE_DECL___BUILTIN_CLZL @HAVE_DECL___BUILTIN_CLZL@
+#cmakedefine HAVE_DECL___BUILTIN_CLZLL @HAVE_DECL___BUILTIN_CLZLL@
+
+#endif // BITCOIN_BITCOIN_CONFIG_H
diff --git a/src/crypto/CMakeLists.txt b/src/crypto/CMakeLists.txt
new file mode 100644
--- /dev/null
+++ b/src/crypto/CMakeLists.txt
@@ -0,0 +1,27 @@
+# Copyright (c) 2017 The Bitcoin developers
+
+project(crypto)
+
+set(CMAKE_CXX_STANDARD 11)
+
+include_directories(
+	..
+	# To access the config.
+	# TODO: Make compat its own lib and just import it.
+	${CMAKE_CURRENT_BINARY_DIR}/..
+	${CMAKE_CURRENT_BINARY_DIR}/../config
+)
+
+# The library
+add_library(crypto
+	aes.cpp
+	chacha20.cpp
+	hmac_sha256.cpp
+	hmac_sha512.cpp
+	ripemd160.cpp
+	sha1.cpp
+	sha256.cpp
+	sha512.cpp
+)
+
+target_compile_definitions(crypto PUBLIC HAVE_CONFIG_H)