diff --git a/src/qt/bitcoingui.cpp b/src/qt/bitcoingui.cpp
--- a/src/qt/bitcoingui.cpp
+++ b/src/qt/bitcoingui.cpp
@@ -285,7 +285,7 @@
         tr("&Receive"), this);
     receiveCoinsAction->setStatusTip(
         tr("Request payments (generates QR codes and %1: URIs)")
-            .arg(GUIUtil::URI_SCHEME));
+            .arg(GUIUtil::bitcoinURIScheme(*cfg)));
     receiveCoinsAction->setToolTip(receiveCoinsAction->statusTip());
     receiveCoinsAction->setCheckable(true);
     receiveCoinsAction->setShortcut(QKeySequence(Qt::ALT + Qt::Key_3));
@@ -410,8 +410,8 @@
 
     openAction = new QAction(platformStyle->TextColorIcon(":/icons/open"),
                              tr("Open &URI..."), this);
-    openAction->setStatusTip(
-        tr("Open a %1: URI or payment request").arg(GUIUtil::URI_SCHEME));
+    openAction->setStatusTip(tr("Open a %1: URI or payment request")
+                                 .arg(GUIUtil::bitcoinURIScheme(*cfg)));
 
     showHelpMessageAction =
         new QAction(platformStyle->TextColorIcon(":/icons/info"),
diff --git a/src/qt/guiutil.h b/src/qt/guiutil.h
--- a/src/qt/guiutil.h
+++ b/src/qt/guiutil.h
@@ -35,7 +35,6 @@
 /** Utility functions used by the Bitcoin Qt UI.
  */
 namespace GUIUtil {
-extern const QString URI_SCHEME;
 
 // Create human-readable string from date
 QString dateTimeStr(const QDateTime &datetime);
@@ -51,6 +50,8 @@
 void setupAddressWidget(QValidatedLineEdit *widget, QWidget *parent);
 void setupAmountWidget(QLineEdit *widget, QWidget *parent);
 
+QString bitcoinURIScheme(const CChainParams &, bool useCashAddr);
+QString bitcoinURIScheme(const Config &);
 // Parse "bitcoincash:" URI into recipient object, return true on successful
 // parsing
 bool parseBitcoinURI(const QString &scheme, const QUrl &uri,
diff --git a/src/qt/guiutil.cpp b/src/qt/guiutil.cpp
--- a/src/qt/guiutil.cpp
+++ b/src/qt/guiutil.cpp
@@ -91,7 +91,6 @@
 #endif
 
 namespace GUIUtil {
-const QString URI_SCHEME("bitcoincash");
 
 QString dateTimeStr(const QDateTime &date) {
     return date.date().toString(Qt::SystemLocaleShortDate) + QString(" ") +
@@ -166,6 +165,17 @@
     widget->setAlignment(Qt::AlignRight | Qt::AlignVCenter);
 }
 
+QString bitcoinURIScheme(const CChainParams &params, bool useCashAddr) {
+    if (!useCashAddr) {
+        return "bitcoincash";
+    }
+    return QString::fromStdString(params.CashAddrPrefix());
+}
+
+QString bitcoinURIScheme(const Config &cfg) {
+    return bitcoinURIScheme(cfg.GetChainParams(), cfg.UseCashAddrEncoding());
+}
+
 static bool IsCashAddrEncoded(const QUrl &uri) {
     const std::string addr = (uri.scheme() + ":" + uri.path()).toStdString();
     auto decoded = cashaddr::Decode(addr);
@@ -250,7 +260,7 @@
     QString ret = info.address;
     if (!cfg.UseCashAddrEncoding()) {
         // prefix address with uri scheme for base58 encoded addresses.
-        ret = (URI_SCHEME + ":%1").arg(ret);
+        ret = (bitcoinURIScheme(cfg) + ":%1").arg(ret);
     }
     int paramCount = 0;
 
diff --git a/src/qt/openuridialog.cpp b/src/qt/openuridialog.cpp
--- a/src/qt/openuridialog.cpp
+++ b/src/qt/openuridialog.cpp
@@ -14,7 +14,7 @@
     : QDialog(parent), ui(new Ui::OpenURIDialog), cfg(cfg) {
     ui->setupUi(this);
 #if QT_VERSION >= 0x040700
-    ui->uriEdit->setPlaceholderText(GUIUtil::URI_SCHEME + ":");
+    ui->uriEdit->setPlaceholderText(GUIUtil::bitcoinURIScheme(*cfg) + ":");
 #endif
 }
 
@@ -28,7 +28,8 @@
 
 void OpenURIDialog::accept() {
     SendCoinsRecipient rcp;
-    if (GUIUtil::parseBitcoinURI(GUIUtil::URI_SCHEME, getURI(), &rcp)) {
+    QString uriScheme = GUIUtil::bitcoinURIScheme(*cfg);
+    if (GUIUtil::parseBitcoinURI(uriScheme, getURI(), &rcp)) {
         /* Only accept value URIs */
         QDialog::accept();
     } else {
@@ -41,6 +42,6 @@
         this, tr("Select payment request file to open"), "", "", nullptr);
     if (filename.isEmpty()) return;
     QUrl fileUri = QUrl::fromLocalFile(filename);
-    ui->uriEdit->setText(GUIUtil::URI_SCHEME + ":?r=" +
+    ui->uriEdit->setText(GUIUtil::bitcoinURIScheme(*cfg) + ":?r=" +
                          QUrl::toPercentEncoding(fileUri.toString()));
 }
diff --git a/src/qt/paymentserver.cpp b/src/qt/paymentserver.cpp
--- a/src/qt/paymentserver.cpp
+++ b/src/qt/paymentserver.cpp
@@ -9,6 +9,7 @@
 #include "optionsmodel.h"
 
 #include "chainparams.h"
+#include "config.h"
 #include "dstencode.h"
 #include "policy/policy.h"
 #include "ui_interface.h"
@@ -211,18 +212,19 @@
         QString arg(argv[i]);
         if (arg.startsWith("-")) continue;
 
+        QString scheme = GUIUtil::bitcoinURIScheme(Params(), false);
         // If the bitcoincash: URI contains a payment request, we are not able
         // to detect the network as that would require fetching and parsing the
         // payment request. That means clicking such an URI which contains a
         // testnet payment request will start a mainnet instance and throw a
         // "wrong network" error.
-        if (arg.startsWith(GUIUtil::URI_SCHEME + ":",
+        if (arg.startsWith(scheme + ":",
                            Qt::CaseInsensitive)) // bitcoincash: URI
         {
             savedPaymentRequests.append(arg);
 
             SendCoinsRecipient r;
-            if (GUIUtil::parseBitcoinURI(GUIUtil::URI_SCHEME, arg, &r) &&
+            if (GUIUtil::parseBitcoinURI(scheme, arg, &r) &&
                 !r.address.isEmpty()) {
                 if (IsValidDestinationString(r.address.toStdString(),
                                              Params(CBaseChainParams::MAIN))) {
@@ -314,8 +316,7 @@
             // constructor is called early in init, so don't use "Q_EMIT
             // message()" here
             QMessageBox::critical(0, tr("Payment request error"),
-                                  tr("Cannot start %1: click-to-pay handler")
-                                      .arg(GUIUtil::URI_SCHEME));
+                                  tr("Cannot start click-to-pay handler"));
         } else {
             connect(uriServer, SIGNAL(newConnection()), this,
                     SLOT(handleURIConnection()));
@@ -391,7 +392,8 @@
     }
 
     // bitcoincash: URI
-    if (s.startsWith(GUIUtil::URI_SCHEME + ":", Qt::CaseInsensitive)) {
+    QString scheme = GUIUtil::bitcoinURIScheme(Params(), false);
+    if (s.startsWith(scheme + ":", Qt::CaseInsensitive)) {
 #if QT_VERSION < 0x050000
         QUrl uri(s);
 #else
@@ -421,7 +423,7 @@
         } else {
             // normal URI
             SendCoinsRecipient recipient;
-            if (GUIUtil::parseBitcoinURI(GUIUtil::URI_SCHEME, s, &recipient)) {
+            if (GUIUtil::parseBitcoinURI(scheme, s, &recipient)) {
                 if (!IsValidDestinationString(
                         recipient.address.toStdString())) {
                     Q_EMIT message(
diff --git a/src/qt/sendcoinsentry.cpp b/src/qt/sendcoinsentry.cpp
--- a/src/qt/sendcoinsentry.cpp
+++ b/src/qt/sendcoinsentry.cpp
@@ -7,6 +7,7 @@
 
 #include "addressbookpage.h"
 #include "addresstablemodel.h"
+#include "config.h"
 #include "guiutil.h"
 #include "optionsmodel.h"
 #include "platformstyle.h"
@@ -35,7 +36,7 @@
         tr("A message that was attached to the %1 URI which will be"
            " stored with the transaction for your reference. Note: "
            "This message will not be sent over the Bitcoin network.")
-            .arg(GUIUtil::URI_SCHEME));
+            .arg(GUIUtil::bitcoinURIScheme(GetConfig())));
 
     setCurrentWidget(ui->SendCoins);
 
diff --git a/src/qt/test/uritests.h b/src/qt/test/uritests.h
--- a/src/qt/test/uritests.h
+++ b/src/qt/test/uritests.h
@@ -15,6 +15,7 @@
     void uriTestsBase58();
     void uriTestsCashAddr();
     void uriTestFormatURI();
+    void uriTestScheme();
 };
 
 #endif // BITCOIN_QT_TEST_URITESTS_H
diff --git a/src/qt/test/uritests.cpp b/src/qt/test/uritests.cpp
--- a/src/qt/test/uritests.cpp
+++ b/src/qt/test/uritests.cpp
@@ -173,11 +173,15 @@
 namespace {
 class UriTestConfig : public DummyConfig {
 public:
-    UriTestConfig(bool useCashAddr) : useCashAddr(useCashAddr) {}
+    UriTestConfig(bool useCashAddr)
+        : useCashAddr(useCashAddr), net(CBaseChainParams::MAIN) {}
     bool UseCashAddrEncoding() const override { return useCashAddr; }
+    const CChainParams &GetChainParams() const override { return Params(net); }
+    void SetChainParams(const std::string &n) { net = n; }
 
 private:
     bool useCashAddr;
+    std::string net;
 };
 
 } // anon ns
@@ -203,3 +207,26 @@
                 "bitcoincash:175tWpb8K1S7NmH4Zx6rewF9WQrcZv245W?message=test");
     }
 }
+
+void URITests::uriTestScheme() {
+    {
+        // cashaddr - scheme depends on selected chain params
+        UriTestConfig config(true);
+        config.SetChainParams(CBaseChainParams::MAIN);
+        QVERIFY("bitcoincash" == GUIUtil::bitcoinURIScheme(config));
+        config.SetChainParams(CBaseChainParams::TESTNET);
+        QVERIFY("bchtest" == GUIUtil::bitcoinURIScheme(config));
+        config.SetChainParams(CBaseChainParams::REGTEST);
+        QVERIFY("bchreg" == GUIUtil::bitcoinURIScheme(config));
+    }
+    {
+        // legacy - scheme is "bitcoincash" regardless of chain params
+        UriTestConfig config(false);
+        config.SetChainParams(CBaseChainParams::MAIN);
+        QVERIFY("bitcoincash" == GUIUtil::bitcoinURIScheme(config));
+        config.SetChainParams(CBaseChainParams::TESTNET);
+        QVERIFY("bitcoincash" == GUIUtil::bitcoinURIScheme(config));
+        config.SetChainParams(CBaseChainParams::REGTEST);
+        QVERIFY("bitcoincash" == GUIUtil::bitcoinURIScheme(config));
+    }
+}