diff --git a/src/init.cpp b/src/init.cpp
--- a/src/init.cpp
+++ b/src/init.cpp
@@ -317,7 +317,7 @@
     GetMainSignals().UnregisterBackgroundSignalScheduler();
     globalVerifyHandle.reset();
     ECC_Stop();
-    node.mempool = nullptr;
+    node.mempool.reset();
     node.chainman = nullptr;
     node.scheduler.reset();
 
@@ -2284,7 +2284,7 @@
     // connection manager, wallet, or RPC threads, which are all started after
     // this, may use it from the node context.
     assert(!node.mempool);
-    node.mempool = &::g_mempool;
+    node.mempool = std::make_unique<CTxMemPool>();
     if (node.mempool) {
         int ratio = std::min<int>(
             std::max<int>(
@@ -2563,7 +2563,7 @@
                 chainman.m_total_coinstip_cache = nCoinCacheUsage;
                 chainman.m_total_coinsdb_cache = nCoinDBCache;
 
-                UnloadBlockIndex(node.mempool);
+                UnloadBlockIndex(node.mempool.get());
 
                 // new CBlockTreeDB tries to delete the existing file, which
                 // fails if it's still open from the previous loop. Close it
diff --git a/src/node/context.h b/src/node/context.h
--- a/src/node/context.h
+++ b/src/node/context.h
@@ -34,8 +34,7 @@
 //! be used without pulling in unwanted dependencies or functionality.
 struct NodeContext {
     std::unique_ptr<CConnman> connman;
-    // Currently a raw pointer because the memory is not managed by this struct
-    CTxMemPool *mempool{nullptr};
+    std::unique_ptr<CTxMemPool> mempool;
     std::unique_ptr<PeerManager> peerman;
     // Currently a raw pointer because the memory is not managed by this struct
     ChainstateManager *chainman{nullptr};
diff --git a/src/node/context.cpp b/src/node/context.cpp
--- a/src/node/context.cpp
+++ b/src/node/context.cpp
@@ -9,6 +9,7 @@
 #include <net.h>
 #include <net_processing.h>
 #include <scheduler.h>
+#include <txmempool.h>
 
 NodeContext::NodeContext() {}
 NodeContext::~NodeContext() {}
diff --git a/src/rest.cpp b/src/rest.cpp
--- a/src/rest.cpp
+++ b/src/rest.cpp
@@ -104,7 +104,7 @@
         RESTERR(req, HTTP_NOT_FOUND, "Mempool disabled or instance not found");
         return nullptr;
     }
-    return node->mempool;
+    return node->mempool.get();
 }
 
 static RetFormat ParseDataFormat(std::string &param,
@@ -446,7 +446,7 @@
     }
     BlockHash hashBlock;
     const CTransactionRef tx =
-        GetTransaction(/* block_index */ nullptr, node->mempool, txid,
+        GetTransaction(/* block_index */ nullptr, node->mempool.get(), txid,
                        Params().GetConsensus(), hashBlock);
     if (!tx) {
         return RESTERR(req, HTTP_NOT_FOUND, hashStr + " not found");
diff --git a/src/rpc/rawtransaction.cpp b/src/rpc/rawtransaction.cpp
--- a/src/rpc/rawtransaction.cpp
+++ b/src/rpc/rawtransaction.cpp
@@ -232,8 +232,9 @@
     }
 
     BlockHash hash_block;
-    const CTransactionRef tx = GetTransaction(
-        blockindex, node.mempool, txid, params.GetConsensus(), hash_block);
+    const CTransactionRef tx =
+        GetTransaction(blockindex, node.mempool.get(), txid,
+                       params.GetConsensus(), hash_block);
     if (!tx) {
         std::string errmsg;
         if (blockindex) {
diff --git a/src/test/util/setup_common.cpp b/src/test/util/setup_common.cpp
--- a/src/test/util/setup_common.cpp
+++ b/src/test/util/setup_common.cpp
@@ -177,7 +177,7 @@
 
     pblocktree.reset(new CBlockTreeDB(1 << 20, true));
 
-    m_node.mempool = &::g_mempool;
+    m_node.mempool = std::make_unique<CTxMemPool>();
     m_node.mempool->setSanityCheck(1.0);
 
     m_node.chainman = &::g_chainman;
@@ -229,8 +229,8 @@
     m_node.connman.reset();
     m_node.banman.reset();
     m_node.args = nullptr;
-    UnloadBlockIndex(m_node.mempool);
-    m_node.mempool = nullptr;
+    UnloadBlockIndex(m_node.mempool.get());
+    m_node.mempool.reset();
     m_node.scheduler.reset();
     m_node.chainman->Reset();
     m_node.chainman = nullptr;
diff --git a/src/validation.h b/src/validation.h
--- a/src/validation.h
+++ b/src/validation.h
@@ -129,7 +129,6 @@
 enum class SynchronizationState { INIT_REINDEX, INIT_DOWNLOAD, POST_INIT };
 
 extern RecursiveMutex cs_main;
-extern CTxMemPool g_mempool;
 typedef std::unordered_map<BlockHash, CBlockIndex *, BlockHasher> BlockMap;
 extern Mutex g_best_block_mutex;
 extern std::condition_variable g_best_block_cv;
diff --git a/src/validation.cpp b/src/validation.cpp
--- a/src/validation.cpp
+++ b/src/validation.cpp
@@ -121,8 +121,6 @@
 
 CFeeRate minRelayTxFee = CFeeRate(DEFAULT_MIN_RELAY_TX_FEE_PER_KB);
 
-CTxMemPool g_mempool;
-
 // Internal stuff
 namespace {
 CBlockIndex *pindexBestInvalid = nullptr;