diff --git a/cmake/platforms/OSX.cmake b/cmake/platforms/OSX.cmake
index e652e12cc..9e587418c 100644
--- a/cmake/platforms/OSX.cmake
+++ b/cmake/platforms/OSX.cmake
@@ -1,44 +1,47 @@
 # Copyright (c) 2017 The Bitcoin developers
 
 set(CMAKE_SYSTEM_NAME Darwin)
 set(TOOLCHAIN_PREFIX x86_64-apple-darwin14)
 
 # On OSX, we use clang by default.
 set(CMAKE_C_COMPILER clang)
 set(CMAKE_CXX_COMPILER clang++)
 
 # On OSX we use various stuff from Apple's SDK.
 set(OSX_SDK_PATH "${CMAKE_CURRENT_SOURCE_DIR}/depends/SDKs/MacOSX10.11.sdk")
 set(CMAKE_OSX_SYSROOT ${OSX_SDK_PATH})
 set(CMAKE_OSX_DEPLOYMENT_TARGET 10.10)
 
 # target environment on the build host system
 #   set 1st to dir with the cross compiler's C/C++ headers/libs
 set(CMAKE_FIND_ROOT_PATH "${CMAKE_CURRENT_SOURCE_DIR}/depends/${TOOLCHAIN_PREFIX};${OSX_SDK_PATH}")
 
 # We also may have built dependencies for the native plateform.
 set(CMAKE_PREFIX_PATH "${CMAKE_CURRENT_SOURCE_DIR}/depends/${TOOLCHAIN_PREFIX}/native")
 
 # modify default behavior of FIND_XXX() commands to
 # search for headers/libs in the target environment and
 # search for programs in the build host environment
 set(CMAKE_FIND_ROOT_PATH_MODE_PROGRAM NEVER)
 set(CMAKE_FIND_ROOT_PATH_MODE_LIBRARY ONLY)
 set(CMAKE_FIND_ROOT_PATH_MODE_INCLUDE ONLY)
 
 # Sysroot clang
 set(OSX_EXTRA_FLAGS
 	" -target ${TOOLCHAIN_PREFIX}"
 	" -mlinker-version=253.9"
 )
 
 string(APPEND CMAKE_C_FLAGS_INIT ${OSX_EXTRA_FLAGS})
 string(APPEND CMAKE_CXX_FLAGS_INIT ${OSX_EXTRA_FLAGS} " -stdlib=libc++")
 
 # Ensure we use an OSX specific version the binary manipulation tools.
 find_program(CMAKE_AR ${TOOLCHAIN_PREFIX}-ar)
 find_program(CMAKE_INSTALL_NAME_TOOL ${TOOLCHAIN_PREFIX}-install_name_tool)
+find_program(CMAKE_LINKER ${TOOLCHAIN_PREFIX}-ld)
 find_program(CMAKE_NM ${TOOLCHAIN_PREFIX}-nm)
+find_program(CMAKE_OBJCOPY ${TOOLCHAIN_PREFIX}-objcopy)
+find_program(CMAKE_OBJDUMP ${TOOLCHAIN_PREFIX}-objdump)
 find_program(CMAKE_OTOOL ${TOOLCHAIN_PREFIX}-otool)
 find_program(CMAKE_RANLIB ${TOOLCHAIN_PREFIX}-ranlib)
 find_program(CMAKE_STRIP ${TOOLCHAIN_PREFIX}-strip)
diff --git a/contrib/gitian-descriptors/gitian-osx.yml b/contrib/gitian-descriptors/gitian-osx.yml
index ea76c80e6..000c31e34 100644
--- a/contrib/gitian-descriptors/gitian-osx.yml
+++ b/contrib/gitian-descriptors/gitian-osx.yml
@@ -1,162 +1,198 @@
 ---
 name: "bitcoin-abc-0.20-osx"
 enable_cache: true
 distro: "debian"
 suites:
 - "buster"
 architectures:
 - "amd64"
 packages:
 - "autoconf"
 - "automake"
 - "bsdmainutils"
 - "ca-certificates"
 - "cmake"
 - "curl"
 - "faketime"
 - "fonts-tuffy"
 - "g++"
 - "git"
 - "imagemagick"
 - "libbz2-dev"
 - "libcap-dev"
 - "librsvg2-bin"
 - "libtiff-tools"
 - "libtinfo5"
 - "libtool"
 - "libz-dev"
 - "ninja-build"
 - "pkg-config"
 - "python3"
 - "python3-dev"
 - "python3-setuptools"
+# FIXME: these dependencies are only required to make CMake happy when building
+# native tools. They can be removed when the `NativeExecutable.cmake` gets
+# improved to avoid requiring all the bitcoin-abc dependencies.
+- "libboost-all-dev"
+- "libevent-dev"
+- "libssl-dev"
 remotes:
 - "url": "https://github.com/Bitcoin-ABC/bitcoin-abc.git"
   "dir": "bitcoin"
 files:
 - "MacOSX10.11.sdk.tar.gz"
 script: |
   WRAP_DIR=$HOME/wrapped
   HOSTS="x86_64-apple-darwin14"
-  CONFIGFLAGS="--enable-reduce-exports --disable-bench --disable-gui-tests GENISOIMAGE=$WRAP_DIR/genisoimage"
+
+  # CMake toolchain file name differ from host name
+  declare -A CMAKE_TOOLCHAIN_FILE
+  CMAKE_TOOLCHAIN_FILE[x86_64-apple-darwin14]=OSX.cmake
+
   FAKETIME_HOST_PROGS=""
   FAKETIME_PROGS="ar ranlib date dmg genisoimage"
 
   export QT_RCC_TEST=1
   export QT_RCC_SOURCE_DATE_OVERRIDE=1
   export GZIP="-9n"
   export TAR_OPTIONS="--mtime="$REFERENCE_DATE\\\ $REFERENCE_TIME""
   export TZ="UTC"
   export BUILD_DIR=`pwd`
   mkdir -p ${WRAP_DIR}
   if test -n "$GBUILD_CACHE_ENABLED"; then
     export SOURCES_PATH=${GBUILD_COMMON_CACHE}
     export BASE_CACHE=${GBUILD_PACKAGE_CACHE}
     mkdir -p ${BASE_CACHE} ${SOURCES_PATH}
   fi
 
   export ZERO_AR_DATE=1
 
   function create_global_faketime_wrappers {
   for prog in ${FAKETIME_PROGS}; do
     echo '#!/usr/bin/env bash' > ${WRAP_DIR}/${prog}
     echo "REAL=\`which -a ${prog} | grep -v ${WRAP_DIR}/${prog} | head -1\`" >> ${WRAP_DIR}/${prog}
     echo 'export LD_PRELOAD=/usr/lib/x86_64-linux-gnu/faketime/libfaketime.so.1' >> ${WRAP_DIR}/${prog}
     echo "export FAKETIME=\"$1\"" >> ${WRAP_DIR}/${prog}
     echo "\$REAL \$@" >> $WRAP_DIR/${prog}
     chmod +x ${WRAP_DIR}/${prog}
   done
   }
 
   function create_per-host_faketime_wrappers {
   for i in $HOSTS; do
     for prog in ${FAKETIME_HOST_PROGS}; do
         echo '#!/usr/bin/env bash' > ${WRAP_DIR}/${i}-${prog}
         echo "REAL=\`which -a ${i}-${prog} | grep -v ${WRAP_DIR}/${i}-${prog} | head -1\`" >> ${WRAP_DIR}/${i}-${prog}
         echo 'export LD_PRELOAD=/usr/lib/x86_64-linux-gnu/faketime/libfaketime.so.1' >> ${WRAP_DIR}/${i}-${prog}
         echo "export FAKETIME=\"$1\"" >> ${WRAP_DIR}/${i}-${prog}
         echo "\$REAL \$@" >> $WRAP_DIR/${i}-${prog}
         chmod +x ${WRAP_DIR}/${i}-${prog}
     done
   done
   }
 
   # Faketime for depends so intermediate results are comparable
   export PATH_orig=${PATH}
   create_global_faketime_wrappers "2000-01-01 12:00:00"
   create_per-host_faketime_wrappers "2000-01-01 12:00:00"
   export PATH=${WRAP_DIR}:${PATH}
 
   cd bitcoin
+  SOURCEDIR=`pwd`
   BASEPREFIX=`pwd`/depends
 
   mkdir -p ${BASEPREFIX}/SDKs
   tar -C ${BASEPREFIX}/SDKs -xf ${BUILD_DIR}/MacOSX10.11.sdk.tar.gz
 
   # Build dependencies for each host
   for i in $HOSTS; do
     make ${MAKEOPTS} -C ${BASEPREFIX} HOST="${i}"
   done
 
   # Faketime for binaries
   export PATH=${PATH_orig}
   create_global_faketime_wrappers "${REFERENCE_DATETIME}"
   create_per-host_faketime_wrappers "${REFERENCE_DATETIME}"
   export PATH=${WRAP_DIR}:${PATH}
 
-  # Create the release tarball using (arbitrarily) the first host
-  ./autogen.sh
-  CONFIG_SITE=${BASEPREFIX}/`echo "${HOSTS}" | awk '{print $1;}'`/share/config.site ./configure --prefix=/
-  make dist
+  mkdir -p source_package
+  pushd source_package
+  cmake -GNinja .. \
+    -DBUILD_BITCOIN_WALLET=OFF \
+    -DBUILD_BITCOIN_ZMQ=OFF \
+    -DBUILD_BITCOIN_ZMQ=OFF \
+    -DBUILD_BITCOIN_SEEDER=OFF \
+    -DBUILD_BITCOIN_CLI=OFF \
+    -DBUILD_BITCOIN_TX=OFF \
+    -DBUILD_BITCOIN_QT=OFF \
+    -DBUILD_LIBBITCOINCONSENSUS=OFF \
+    -DENABLE_QRCODE=OFF \
+    -DENABLE_UPNP=OFF
+  ninja package_source
   SOURCEDIST=`echo bitcoin-abc-*.tar.gz`
+  mv ${SOURCEDIST} ..
+  popd
   DISTNAME=`echo ${SOURCEDIST} | sed 's/.tar.*//'`
 
   # Correct tar file order
   mkdir -p temp
   pushd temp
   tar xf ../$SOURCEDIST
   find bitcoin-abc-* | sort | tar --no-recursion --mode='u+rw,go+r-w,a+X' --owner=0 --group=0 -c -T - | gzip -9n > ../$SOURCEDIST
   popd
 
   ORIGPATH="$PATH"
   # Extract the release tarball into a dir for each host and build
   for i in ${HOSTS}; do
     export PATH=${BASEPREFIX}/${i}/native/bin:${ORIGPATH}
     mkdir -p distsrc-${i}
     cd distsrc-${i}
     INSTALLPATH=`pwd`/installed/${DISTNAME}
     mkdir -p ${INSTALLPATH}
     tar --strip-components=1 -xf ../$SOURCEDIST
 
-    CONFIG_SITE=${BASEPREFIX}/${i}/share/config.site ./configure --prefix=/ --disable-ccache --disable-maintainer-mode --disable-dependency-tracking ${CONFIGFLAGS}
-    make ${MAKEOPTS}
-    make install-strip DESTDIR=${INSTALLPATH}
+    cmake -GNinja .. \
+      -DCMAKE_TOOLCHAIN_FILE=${SOURCEDIR}/cmake/platforms/${CMAKE_TOOLCHAIN_FILE[${i}]} \
+      -DCLIENT_VERSION_IS_RELEASE=ON \
+      -DENABLE_REDUCE_EXPORTS=ON \
+      -DCMAKE_INSTALL_PREFIX=${INSTALLPATH} \
+      -DCCACHE=OFF \
+      -DGENISOIMAGE_EXECUTABLE="${WRAP_DIR}/genisoimage"
+
+    ninja
+    ninja install
+
+    export PYTHONPATH="${BASEPREFIX}/${i}/native/lib/python3/dist-packages:${PYTHONPATH}"
+    ninja osx-deploydir
 
-    make osx_volname
-    make deploydir
     OSX_VOLNAME="$(cat osx_volname)"
     mkdir -p unsigned-app-${i}
     cp osx_volname unsigned-app-${i}/
     cp contrib/macdeploy/detached-sig-apply.sh unsigned-app-${i}
     cp contrib/macdeploy/detached-sig-create.sh unsigned-app-${i}
     cp ${BASEPREFIX}/${i}/native/bin/dmg ${BASEPREFIX}/${i}/native/bin/genisoimage unsigned-app-${i}
     cp ${BASEPREFIX}/${i}/native/bin/${i}-codesign_allocate unsigned-app-${i}/codesign_allocate
     cp ${BASEPREFIX}/${i}/native/bin/${i}-pagestuff unsigned-app-${i}/pagestuff
     mv dist unsigned-app-${i}
     pushd unsigned-app-${i}
     find . | sort | tar --no-recursion --mode='u+rw,go+r-w,a+X' --owner=0 --group=0 -c -T - | gzip -9n > ${OUTDIR}/${DISTNAME}-osx-unsigned.tar.gz
     popd
 
-    make deploy
+    ninja osx-dmg
     ${WRAP_DIR}/dmg dmg "${OSX_VOLNAME}.dmg" ${OUTDIR}/${DISTNAME}-osx-unsigned.dmg
 
     cd installed
-    find . -name "lib*.la" -delete
-    find . -name "lib*.a" -delete
-    rm -rf ${DISTNAME}/lib/pkgconfig
-    find ${DISTNAME} | sort | tar --no-recursion --mode='u+rw,go+r-w,a+X' --owner=0 --group=0 -c -T - | gzip -9n > ${OUTDIR}/${DISTNAME}-${i}.tar.gz
+    # The install/strip target should do exactly that. However there is a bug in
+    # in the Buster CMake version that causes strip to be called with the wrong
+    # parameters when an Apple strip tool is used. This is fixed starting with
+    # CMake versions >= 3.14, see:
+    # https://gitlab.kitware.com/cmake/cmake/merge_requests/2892
+    find -path "*.app*" -type f -executable -exec mv {} ${DISTNAME}/bin/bitcoin-qt \;
+    find ${DISTNAME}/bin -type f -executable -exec ${i}-strip -u -r {} \;
+    find ${DISTNAME}/lib -type f -executable -exec ${i}-strip -x {} \;
+    find ${DISTNAME} -not -path "*.app*" | sort | tar --no-recursion --mode='u+rw,go+r-w,a+X' --owner=0 --group=0 -c -T - | gzip -9n > ${OUTDIR}/${DISTNAME}-${i}.tar.gz
     cd ../../
   done
   mkdir -p $OUTDIR/src
   mv $SOURCEDIST $OUTDIR/src
   mv ${OUTDIR}/${DISTNAME}-x86_64-*.tar.gz ${OUTDIR}/${DISTNAME}-osx64.tar.gz