diff --git a/depends/config.site.in b/depends/config.site.in
index a2da960819..c24e2fe82a 100644
--- a/depends/config.site.in
+++ b/depends/config.site.in
@@ -1,99 +1,99 @@
 depends_prefix=$(cd `dirname ${ac_site_file}`/..; pwd -P)
 
 cross_compiling=maybe
 host_alias=@HOST@
 ac_tool_prefix=${host_alias}-
 
 if test -z $with_boost; then
   with_boost=$depends_prefix
 fi
 if test -z $with_qt_plugindir; then
   with_qt_plugindir=$depends_prefix/plugins
 fi
 if test -z $with_qt_translationdir; then
   with_qt_translationdir=$depends_prefix/translations
 fi
 if test -z $with_qt_bindir; then
   with_qt_bindir=$depends_prefix/native/bin
 fi
 if test -z $with_protoc_bindir; then
   with_protoc_bindir=$depends_prefix/native/bin
 fi
 
 
 if test -z $enable_wallet && test -n "@no_wallet@"; then
   enable_wallet=no
 fi
 
 if test -z $with_miniupnpc && test -n "@no_upnp@"; then
   with_miniupnpc=no
 fi
 
 if test -z $with_gui && test -n "@no_qt@"; then
   with_gui=no
 fi
 
 if test x@host_os@ = xdarwin; then
   BREW=no
   PORT=no
 fi
 
 if test x@host_os@ = xmingw32; then
   if test -z $with_qt_incdir; then
     with_qt_incdir=$depends_prefix/include
   fi
   if test -z $with_qt_libdir; then
     with_qt_libdir=$depends_prefix/lib
   fi
 fi
 
 PATH=$depends_prefix/native/bin:$PATH
 PKG_CONFIG="`which pkg-config` --static"
 
 # These two need to remain exported because pkg-config does not see them
 # otherwise. That means they must be unexported at the end of configure.ac to
 # avoid ruining the cache. Sigh.
 
 export PKG_CONFIG_LIBDIR=$depends_prefix/lib/pkgconfig
 export PKG_CONFIG_PATH=$depends_prefix/share/pkgconfig
 
 CPPFLAGS="-I$depends_prefix/include/ $CPPFLAGS"
 LDFLAGS="-L$depends_prefix/lib $LDFLAGS"
 
 CC="@CC@"
 CXX="@CXX@"
 OBJC="${CC}"
 CCACHE=$depends_prefix/native/bin/ccache
-PYTHONPATH=$depends_prefix/native/lib/python/dist-packages:$PYTHONPATH
+PYTHONPATH=$depends_prefix/native/lib/python3/dist-packages:$PYTHONPATH
 
 if test -n "@AR@"; then
   AR=@AR@
   ac_cv_path_ac_pt_AR=${AR}
 fi
 
 if test -n "@RANLIB@"; then
   RANLIB=@RANLIB@
   ac_cv_path_ac_pt_RANLIB=${RANLIB}
 fi
 
 if test -n "@NM@"; then
   NM=@NM@
   ac_cv_path_ac_pt_NM=${NM}
 fi
 
 if test -n "@debug@"; then
   enable_reduce_exports=no
 fi
 
 if test -n "@CFLAGS@"; then
   CFLAGS="@CFLAGS@ $CFLAGS"
 fi
 if test -n "@CXXFLAGS@"; then
   CXXFLAGS="@CXXFLAGS@ $CXXFLAGS"
 fi
 if test -n "@CPPFLAGS@"; then
   CPPFLAGS="@CPPFLAGS@ $CPPFLAGS"
 fi
 if test -n "@LDFLAGS@"; then
   LDFLAGS="@LDFLAGS@ $LDFLAGS"
 fi
diff --git a/depends/packages/native_biplist.mk b/depends/packages/native_biplist.mk
index 5f247e9bf3..c3054cbd1a 100644
--- a/depends/packages/native_biplist.mk
+++ b/depends/packages/native_biplist.mk
@@ -1,15 +1,15 @@
 package=native_biplist
 $(package)_version=1.0.3
 $(package)_download_path=https://bitbucket.org/wooster/biplist/downloads
 $(package)_file_name=biplist-$($(package)_version).tar.gz
 $(package)_sha256_hash=4c0549764c5fe50b28042ec21aa2e14fe1a2224e239a1dae77d9e7f3932aa4c6
-$(package)_install_libdir=$(build_prefix)/lib/python/dist-packages
+$(package)_install_libdir=$(build_prefix)/lib/python3/dist-packages
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef
diff --git a/depends/packages/native_ds_store.mk b/depends/packages/native_ds_store.mk
index 116fa25d38..f99b689ecd 100644
--- a/depends/packages/native_ds_store.mk
+++ b/depends/packages/native_ds_store.mk
@@ -1,16 +1,16 @@
 package=native_ds_store
 $(package)_version=1.1.2
 $(package)_download_path=https://github.com/al45tair/ds_store/archive/
 $(package)_file_name=v$($(package)_version).tar.gz
 $(package)_sha256_hash=3b3ecb7bf0a5157f5b6010bc3af7c141fb0ad3527084e63336220d22744bc20c
-$(package)_install_libdir=$(build_prefix)/lib/python/dist-packages
+$(package)_install_libdir=$(build_prefix)/lib/python3/dist-packages
 $(package)_dependencies=native_biplist
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef
diff --git a/depends/packages/native_mac_alias.mk b/depends/packages/native_mac_alias.mk
index 306c835656..e60b99dccc 100644
--- a/depends/packages/native_mac_alias.mk
+++ b/depends/packages/native_mac_alias.mk
@@ -1,15 +1,15 @@
 package=native_mac_alias
 $(package)_version=2.0.7
 $(package)_download_path=https://github.com/al45tair/mac_alias/archive/
 $(package)_file_name=v$($(package)_version).tar.gz
 $(package)_sha256_hash=6f606d3b6bccd2112aeabf1a063f5b5ece87005a5d7e97c8faca23b916e88838
-$(package)_install_libdir=$(build_prefix)/lib/python/dist-packages
+$(package)_install_libdir=$(build_prefix)/lib/python3/dist-packages
 
 define $(package)_build_cmds
-    python setup.py build
+    python3 setup.py build
 endef
 
 define $(package)_stage_cmds
     mkdir -p $($(package)_install_libdir) && \
-    python setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
+    python3 setup.py install --root=$($(package)_staging_dir) --prefix=$(build_prefix) --install-lib=$($(package)_install_libdir)
 endef