Berkeley DB changed it's internal format after 4.8 . So any DB created with 5.3 cannot be read with software using 4.8 . Historically, Bitcoin ABC ensure that the version used is 4.8 unless specified otherwize. This is cumbersome as this version is relatively old. In addition, itis fairly common that bitcoin is packaed using a more recent version by default (for instance on ubuntu/debian).
As a result, it seems like a better strategy to ensure the version used is 5.3 or more recent going forward.